Convergence of YAP/TAZ, TEAD and TP63 activity is associated with bronchial premalignant severity and progression
Abstract Background Bronchial premalignant lesions (PMLs) are composed primarily of cells resembling basal epithelial cells of the airways, which through poorly understood mechanisms have the potential to progress to lung squamous cell carcinoma (LUSC).Despite ongoing efforts that have mapped gene expression and cell diversity across bronchial PML